Abstract
Consecutive formation constants of metal complexes of isonicotinoylhydrazine (INH) and related compounds were determined by the pH titration method. The calculation was performed by an electronic computer applying the iterative approximation method from the data of titration curves of various ratio of ligand to metal ion, pKa values of ligands, and hydrolysis constants of metal ions which were also determined by pH titration. The constants thus obtained for 1 : 1 complexes and chelates were plotted against the pKa values, and some interesting relationship suggesting the reaction mechanism of complex formation were found.
