Syntheses and Antiviral Effects of 3-Amino-6-alkyl-as-triazin-5-ol Derivatives.

Abstract

The thirteen compounds of amidinohydrazone of α-oxocarboxylic acid and 3-amino-6-alkyl-as-triazin-5-ol were synthesized and tested as to their antiviral activity. Only amidinohydrazone of 2-oxovaleric acid was found effective on common cold virus. Also, it was revealed that the possible existence of the tautomers of 3-amino-6-alkyl-as-triazin-5-ol in the ground state should be in form of keto and imino.