Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Ind. -N-Alkylation of Tryptophan and Synthesis of 1-Alkyltryptophan Hydrazides
山田 俊一塩入 孝之板谷 泰助原 健松枝 礼
著者情報
ジャーナル フリー

1965 年 13 巻 1 号 p. 88-93

詳細
抄録
A convenient method for the synthesis of 1-alkyltryptophans is described. The proof of ind. -N-alkylation was obtained from several data. Effect of 1-alkyl substitution of indole was observed on the ultraviolet spectra of 1-alkytryptophans. It was confirmed by debenzylation of L-1-benzyltryptophan in liquid ammonia that no racemization had occurred in the alkylation. 1-Alkyltryptophans were converted to hydrazides via methyl ester hydrochlorides in good yields.
著者関連情報
© The Pharmaceutical Society of Japan
前の記事 次の記事
feedback
Top