Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Trisulfation of Hexoses by Means of Concentrated Sulfuric Acid
KIYOSHI TAKIURAHIDETAKA YUKISUSUMU HONDAYASUO KOJIMALANYU CHEN
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1970 Volume 18 Issue 3 Pages 429-435

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Abstract
Sulfation of D-glucose, D-galactose, D-mannose and D-fructose with concentrated sulfuric acid yielded pure trisulfates of these hexoses. The situation of the sulfate groups in these trisulfates was decided on the basis of the behavior to oxidizing agents, methylation analyses and periodate oxidation. 1, 3, 6-Substitution for the aldohexoses and 1, 2, 4-substitution for the ketohexose were established.
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© The Pharmaceutical Society of Japan
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