Abstract
Sulfation of D-glucose, D-galactose, D-mannose and D-fructose with concentrated sulfuric acid yielded pure trisulfates of these hexoses. The situation of the sulfate groups in these trisulfates was decided on the basis of the behavior to oxidizing agents, methylation analyses and periodate oxidation. 1, 3, 6-Substitution for the aldohexoses and 1, 2, 4-substitution for the ketohexose were established.