Rate of Gastric Emptying of Phenol Red in a Rabbit

Abstract

The purpose of this study was to determine the gastric emptying pattern of Phenol Red in solution form and to consider the apparent effect of few drugs on the rate of emptying through the pylorus of orally administered Phenol Red using rabbits. It was found that the gastric emptying of Phenol Red was regarded as exponential in form and the gastric response of rabbits was almost unchanged for two months. Aminopyrine delayed considerably the gastric emptying of Phenol Red from kinetical point of view. Caffeine which has increasing effect on human gastric secretion did not affect the rate of emptying of Phenol Red.