Abstract
Cytidine 5'-monophosphate was reacted with p-toluenesulfonyl chloride in dioxanesodium hydroxide solution. Ion exchange column chromatography of the nucleotides and analysis of each fraction by paper chromatography and paper electrophoresis showed presence of 5'-cytidine 5'-monophosphate, 2, 2'-cyclo-arabinosvlcytosine 5'-monophosphate, arabinosylcytosine 5'-monophosphate, 2, 2'-cyclo-3'-tosylarabinosylcytosine 5'-monophosphate, 2, 3'-cyclo-lyxosylcytosine 5'-monophosphate, 2', 3'-epoxylyxofuranosylcytosine 5'-monophosphate and lyxofuranosylcytosine 5'-monophosphate. 2, 2'-Cycloarabinosylcytosine 5'-monophosphate was isolated in 33% yield.
