Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
A Photochemical Preparation of N-Substituted Pyrroles from Pyridazine N-Oxides
土屋 隆新井 平八郎井下田 浩
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1973 年 21 巻 7 号 p. 1516-1519

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抄録
Irradiation of a mixture of pyridazine N-oxide (I) and primary amine dissolved in dichloromethane resulted in the formation of the corresponding N-substituted pyrrole. Thus, from pyridazine 1-oxide (IA), N-substituted pyrroles (VIIAa-d) were obtained. From 6-methylpyridazine 1-oxide (IB), N-substituted 2-methylpyrroles (VIIBa-d) were obtained. From 3-methylpyridazine 1-oxide (IC), 2-methylpyrroles (VIIB) and their isomers, 3-methylpyrroles (VIIIC) were obtained.
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© The Pharmaceutical Society of Japan
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