Studies on Peptides. XLVI. Synthesis of Human Type Corticotropinlike Intermediate Lobe Peptide (CLIP)

Abstract

The docosapeptide, H-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Gln-Ala-Phe-Pro-Leu-Glu-Phe-OH, corresponding to positions 18 to 39 of human ACTH (human type corticotropin-like intermediate lobe peptide, CLIP) was synthesized by the conventional method and by the fragment condensation procedure on a polymer support.