Synthesis of Some Cyclic Derivatives of Spermine and Spermidine

Abstract

Some cyclic derivatives of spermine and spermidine, 1, 5, 8, 12-tetraazacyclohexadecane 7, 1, 5, 9, 13-tetraazacycloheptadecane 9, and 1, 5, 9-triazacyclotridecane 11 were synthesized as part of our studies on the functions of natural polyamines and the effects of structural modification of the biological activities.