Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
The Study of Elements in Organisms by Neutron Activation Analysis. III. The Distribution of Trace Elements in Various Organs of Normal Rat and in Cell Fractions of Rat Liver
MASAKI SHINOGIKAYOKO FUKUDAMIYUKI NAKAZAWAITSUHIKO MORI
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1980 Volume 28 Issue 7 Pages 2094-2100

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Abstract

The use of standard reference materials (SRM's) i. e. NBS orchard leaves and bovine liver, as multielemental irradiation standards in NAA is discussed. This technique was applied to the analysis of trace elements in various organs of the rat and in cell fractions of the rat liver. Nondestructive neutron activation analysis was carried out to determine 13 elements (As, Br, Co, Cr, Cs, Fe, K, Mn, Na, Rb, Sc, Se and Zn) in each sample. High concentrations of several elements were found in some organs of the rat. In particular, the testes contained many elements at high concentrations, while the contents of all elements were highest in the liver. The mean concentrations of elements in various organs of the rat were classified roughly, and the elemental concentrations in cell fractions of the rat liver are discussed. The cytosol contained the greatest quantities of the elements, with the exception of Mn.

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© The Pharmaceutical Society of Japan
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