Studies on Lipid Peroxidation in Biological Systems. I. Effects of Various Factors on Lipid Peroxide Level in Blood

Abstract

Plasma lipid peroxide concentration has been demonstrated to vary with the species, strain, sex and age of laboratory animals as well as with conditions of starvation and stress. Mice showed remarkably high plasma TBA levels as compared with other species of animals, and the ICR and ddY strains of mice, among other strains, may be useful as experimental models, since they proved to have relatively slight interindividual differences. The data obtained indicate that great care in the management and experimental handling of laboratory animals are essential because of the enhancing effect of stress on the plasma TBA level.