Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
THE CONVERSION OF PSEUDOKOBUSINE TO KOBUSINE
Shinichiro Sakai, Ichiro Yamamoto, Toshihiko Okamoto
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Keywords: ring closing reaction
JOURNAL FREE ACCESS

1982 Volume 30 Issue 12 Pages 4583-4584

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Abstract

A six step conversion of pseudokobusine (I) to kobusine (Vb) proceeding via the ring opening compound (IIIa, b, c) is presented. The C-15 secondary alcohol group of pseudokobusine (I) was found to have the R configuration.

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© The Pharmaceutical Society of Japan
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