Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reaction of β-Aminocrotonamide with N-Acylated Amino Acid Esters to give 2-Acylaminoalkyl-6-methylpyrimidin-4 (3H)-ones and Their Ring Closure with Polyphosphoric Acid (PPA)
片桐 信弥腰原 朱美厚海 修吾加藤 鉄三
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キーワード: ^1H-NMR
ジャーナル フリー

1983 年 31 巻 7 号 p. 2288-2295

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抄録
Reaction of β-aminocrotonamide with N-acylated amino acid esters in the presence of sodium methoxide gave 2-acylaminoalkyl-6-methylpyrimidin-4 (3H)-ones, some of which, on treatment with polyphosphoric acid (PPA), were transformed into imidazo [1, 5-a] pyrimidines and imidazo [4, 5-b] pyridines.
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© The Pharmaceutical Society of Japan
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