BORONATION-THALLATION, A NEW APPROACH TO THE SYNTHESIS OF INDOLES HAVING ARYL AND/OR A HETEROARYL SUBSTITUENT AT THE 4-POSITION

Abstract

A new coupling reaction for unsymmetrical biaryls was developed and applied successfully to the syntheses of 4-arylindoles. Photoreaction of 4-halogenoindoles also proved to be a useful method for preparing 4-substituted indoles. An alternative method for synthesizing 4-(3-pyridyl)-3-indolecarbaldehyde is also reported.