The Constituents of Schizandra chinensis BAILL. XV. Isolation and Structure Determination of Two New Lignans, Gomisin S and Gomisin T

Abstract

Two new dibenzocyclooctadiene lignans, gomisin S (1) and gomisin T (2), were isolated from the fruits of Schizandra chinensis BAILL.(Schizandraceae). On the basis of spectral methods and chemical transformations, the structures of 1 and 2 were elucidated as (6S, 7S, 8S, S-biar)-5, 6, 7, 8-tetrahydro-1, 2, 10, 11, 12-pentamethoxy-6, 7-dimethy1-3, 8-dibenzo [a, c] cyclooctenediol and (6S, 7S, R-biar)-5, 6, 7, 8-tetrahydro-1, 2, 10, 11, 12-pentamethoxy-6, 7-dimethy1-3, 7-dibenzo [a, c] cyclooctenediol, respectively.