Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
A New Cytotoxic Chlorine-Containing Polyacetylene from the Callus of Panax ginseng
YASUO FUJIMOTO, MITSURU SATOH
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Keywords: Panax ginseng, Araliaceae, callus, chlorine-containing C17-polyacetylene, 1-chloro-9, 10-epoxy-4, 6-heptadecadiyne-2, 3-diol, anticancer activity
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1988 Volume 36 Issue 10 Pages 4206-4208

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Abstract

A new chlorine-containing polyacetylene (3) and panaxydol (4) have been isolated from the callus of Panax ginseng, The structure of 3 was confirmed by its 1H-nuclear magnetic resonance (NMR), 13C-NMR and mass spectral data. The new acetylene exhibited growth inhibition against leukemia cells (L-1210) in tissue culture.

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© The Pharmaceutical Society of Japan
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