SYNTHESES OF (+)-CYCLARADINE AND (+)-9-PSEUDO-β-L-XYLOFURANOSYLADENINE, TWO OPTICALLY ACTIVE CYCLOPENTANE ANALOGS OF NUCLEOSIDE

Masayuki YOSHIKAWA; Takahiko NAKAE; Bae Cheon CHA; Yoshihiro YOKOKAWA; Isao KITAGAWA

doi:10.1248/cpb.37.545

Masayuki YOSHIKAWA, Takahiko NAKAE, Bae Cheon CHA, Yoshihiro YOKOKAWA, Isao KITAGAWA

Author information

Keywords: (+)-cyclaradine, (+)-9-pseudo-β-L-xylofuranosyladenine, nucleoside cyclopentane analog optically activ, pseudo-glycoside, nitro-cyclopentene, Michael-type addition reaction, antiviral agent, antitumor activity, D-glucose

JOURNAL FREE ACCESS

1989 Volume 37 Issue 2 Pages 545-547

DOI https://doi.org/10.1248/cpb.37.545

Details

Abstract

Two optically active cyclopentane analogs of nucleoside, (+)-cyclaradine and (+)-9-pseudo-β-L-xylofuranosyladenine, were synthesized from N⁶-benzoyladenine and nitro-cyclopentenes derived from pseudo-nitrofuranoses through a Michael-type addition reaction.

Corresponding author

Register with J-STAGE for free!