Synthesis of Nucleosides and Related Compounds. XXII. Carbocyclic Analogues of Thymidine and Related compounds from 2-Azabicyclo[2.2.1]hept-5-en-3-ones

Nobuya KATAGIRI; Masahiro NOMURA; Makoto MUTO; Chikara KANEKO

doi:10.1248/cpb.39.1682

片桐信弥, 野村昌弘, 武藤真, 金子主税

著者情報

キーワード: reductive amido bond cleavage; sodium borohydride, carbocyclic nucleoside, 2-azabicyclo[2.2.1]hept-5-en-3-one, epoxidationl, cyclonucleoside, carbocyclic thymidine

ジャーナルフリー

1991 年 39 巻 7 号 p. 1682-1688

DOI https://doi.org/10.1248/cpb.39.1682

詳細

抄録

Reductive amido bond cleavage reaction, previously elaborated by our laboratory for the synthesis of carbocyclic ribothymidine from readily available 2-azabicyclo[2.2.1]hept-5-en-3-one, was successfully applied to the synthesis of carbocyclic analogues of thymidine and related compounds.

責任著者(Corresponding author)

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