Studies on Immunostimulating Derivatives : Synthesis of Some Pyrrolo[1, 2-c]pyrimidines

Abstract

In a search for potential immunomodulating agents novel pyrrolo[1, 2-c]pyrimidines were synthesized and their structures elucidated by spectroscopic means. Unfortunately, most of them were cytotoxic and devoid of effects on Tlymphocyte lymphoblastic transformation. Furthermore, they were inactive in the locomotor activity test in mice.