Antibacterial Effect of Lichen Substances and Related Compounds. VIII. Some Observations on Inactivation of Antitubercular Activity by Surface Active Agents and Serum.

Abstract

Influence of some agents, such as Tween 80 and serum albumin, on the antibacterial activity of eight compounds including dibenzofuran derivatives was examined. Interaction between antibacterial agents and Tween 80 or serum albumin was also examined by solubility and equilibrium dialysis, and some discussions were made on the cause of decrease of antibacterial action by the addition of surface active agents or serum albumin.