Detoxication and Excretion of Radioactive Strontium. II. Effect of Several Organic Acids having Chelating Ability.

Abstract

Effect of tricarballylate, citraconate, tartrate, lactate, and citrate, which are able to form chelating complex with strontium, on the distribution of parenterally administered radioactive strontium was examined, and it was indicated that all of these organic acids markedly decreased skeletal depostion of radiostrontium and four acids other than citrate markedly increased radiostrontium in the blood serum and soft tissues.