Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Carcinostatic Substances. XXIII. Correlation between Anti-tumor and leucopenia-inducing Effects of Alkylating Agents
Morizo IshidateYoshio SakuraiEiichi Matsui
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1960 Volume 8 Issue 2 Pages 89-94

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Abstract
Each of 10 different derivatives of nitrogen mustard was tested on 12 Yoshida sarcoma rats for their life-prolongation and leucopenia-inducing effects. It was found that some showed a very strong effect of life-prolongation on the tumor rats, although the leucopenia-inducing effect of such compounds was quite equal to those of other compounds.
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© The Pharmaceutical Society of Japan
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