Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
4, 5-Disubstituted Pyridazines. VIII. Hydrolysis of 2-Phenyl-6-chlorooxazolo[5, 4-c]pyridazine
Tsukasa Kuraishi
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1960 Volume 8 Issue 6 Pages 553-554

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Abstract

1) 4-Benzamido-6-chloro-3-pyridazinol (IV) was obtained from 4-amino-6-chloro-3-pyridazinol (III) by heating with benzoyl chloride under reflux in the presence of pyridine or nitrobenzene as a solvent. 2) 2-Phenyl-6-chlorooxazolo[5, 4-c]pyridazine (I) yielded (III) and (IV) on heating with sodium hydroxide solution and hydrochloric acid, respectively.

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© The Pharmaceutical Society of Japan
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