抄録
The daily administration of β-estradiol benzoate (50μg or I mg) to hypophysectomized female rats for five consecutive days did not markedly alter 131I uptake by the thyroid gland. Estrogen or PMS increased thyroid uptake of 131I in TSH treated hypophysectomized rats. Similar results were obtained with estrogen but not PMS in hypophysectomized and oophorectomized animals. These observations show that estrogen can potentiate the TSH induced uptake of 131I by an extrapituitary mechanism.