Clinical Studies on Thyroid CT Number in Chronic Thyroiditis
キーワード:
Thyroid CT,
Chronic thyroiditis
1994 年 41 巻 1 号 p. 19-23
詳細
1994 年 41 巻 1 号 p. 19-23
The purpose of the present study is to investigate by a computed tomography (CT) thyroid CT number (Hounsfield units; H.U.) in chronic thyroiditis (CH).
The correlation of the CT value with the concentration of KI solution in the test tube of thyroid phantom for thyroid scintigram was linear. No significant correlation between thyroid CT number and the urinary iodine concentration was also observed in 36 patients with CH. A mean thyroid CT number (±SD) of 81±24 H.U. in 155 patients with CH was significantly (P<0.001) lower than 125±18 H.U. in 95 normal subjects. The patients with CH could be arbitrarily divided into 3 groups according to the decrease in their thyroid CT number: normal (N) group (_??_88 H.U.), moderately decreased (MD) group (70-87 H.U.) and the greately decreased (GD) group (<70 H.U.). There was a significant difference in the thyroid volume among 21.2±9.1cm3 in the N group, 32.2±18.1 in the MD group (P<0.05 vs. N group) and 43.6±23.3 in the GD group (P<0.01 vs. N and MD group). The mean serum TSH concentration of 38.95±54.61μU/ml in the SD group was significantly (P<0.01) higher than either 4.11±3.64 in the MD group or 2.00±1.43 in the N group. The serum TSH level in the MD group differed significantly (P<0.05) from that of the N group.
Hypothyroidism characterized by low serum FT4 (<0.8ng/dl) and very high serum TSH was observed in none in the N group, in 2 (7.1%) of 28 cases in the MD group and in 16 (33.3%) of 48 cases in the GD group. And latent hypothyroidism characterized by an increase in serum TSH levels (_??_5μU/ml) and normal concentrations of thyroid hormones was found in 2 (5.1%) of 39 cases in the N group, 5 (17.9%) in the MD group and 16 (33.3%) of the GD group. There was a significant (P<0.005) difference in multiple chi-square analysis in the comparison between the GD group and the N group or MD group. The frequency of higher titers of antimicrosomal Ab and antithyroglobulin Ab seemed to be correlated with the amount of decrease in the thyroid CT number. In conclusion, there was a significant correlation between the thyroid CT number and the severity of chronic thyroiditis.
