Effect of Dietary Lipid Type on the Enhancement of Swimming Endurance of Mice by L-Lactic Acid

Abstract

Mice fed either a diet containing 6% lard, fish oil or Erabu sea snake lipids for 16 weeks were intraperitoneally injected L-lactic acid or glucose (25 mg/kg) following injection of physiological saline and subjected to swimming tests at 30 min after each injection. The swimming time ratio of lactic acid to saline injections was greater in mice fed sea snake lipids than those fed lard (p < 0.01) or fish oil (p < 0.05), and significantly greater than that of glucose to saline injections only in mice fed sea snake lipids (p < 0.01) but not those fed lard or fish oil. Increased endurance by injected glucose was not observed in mice fed any of the diets. These results indicate that dietary lipid type affects the endurance of mice injected with L-lactic acid, and Erabu sea snake lipids may contain factors that regulate lactic acid metabolism effectively.