Hypoxia Tolerance and Fatigue Relief Produced by Lepidium meyenii and its Water-soluble Polysaccharide in Mice

Xiao-Feng Chen; Yan-Yun Liu; Min-Jie Cao; Ling-Jing Zhang; Le-Chang Sun; Wen-Jin Su; Guang-Ming Liu

doi:10.3136/fstr.22.611

Original papers

Hypoxia Tolerance and Fatigue Relief Produced by Lepidium meyenii and its Water-soluble Polysaccharide in Mice

Xiao-Feng Chen, Yan-Yun Liu, Min-Jie Cao, Ling-Jing Zhang, Le-Chang Sun, Wen-Jin Su, Guang-Ming Liu

著者情報

Xiao-Feng Chen
College of Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial, Engineering Technology Research Center of Marine Functional Food, Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Jimei University
Yan-Yun Liu
Xiamen Everbright Biotechnology Ltd
Min-Jie Cao
College of Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial, Engineering Technology Research Center of Marine Functional Food, Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Jimei University
Ling-Jing Zhang
College of Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial, Engineering Technology Research Center of Marine Functional Food, Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Jimei University
Le-Chang Sun
College of Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial, Engineering Technology Research Center of Marine Functional Food, Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Jimei University
Wen-Jin Su
College of Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial, Engineering Technology Research Center of Marine Functional Food, Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Jimei University
Guang-Ming Liu 責任著者
College of Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial, Engineering Technology Research Center of Marine Functional Food, Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Jimei University

キーワード: maca (Lepidium meyenii), maca aqueous extracts, maca water-soluble polysaccharide, relieve fatigue, hypoxia tolerance, BALB/c mice

ジャーナルオープンアクセス HTML

2016 年 22 巻 5 号 p. 611-621

DOI https://doi.org/10.3136/fstr.22.611

詳細

抄録

The aim of the present study was to investigate the effects of Lepidium meyenii (maca) on hypoxia tolerance and fatigue relief, and to determine its active constituents. The results showed that, in the mouse model, maca powder could significantly prolong hypoxia time (HT) and forced swim time (FST) and optimize blood sugar ratio (BSR), liver glycogen (LG), muscle glycogen (MG), blood lactic acid, and lactic dehydrogenase. Based on these results, aqueous extracts and maca water-soluble polysaccharide (MWP) were isolated. The total sugar content of MWP is 90.41 ± 2.55%, and the main monosaccharide component is glucose (79.88%). In the mouse model, HT (40.76 ± 7.97 min), FST (48.32 ± 10.76 min), BSR (4.49 ± 4.04%), LG (11.27 ± 0.61 mg/g), and MG (1.45 ± 0.17 mg/g) were all significantly enhanced in groups given maca powder compared to the control group (p < 0.05). In summary, maca is effective in improving hypoxia tolerance and relieving fatigue, and MWP is the active substance.

責任著者(Corresponding author)

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