2024 Volume 30 Issue 6 Pages 647-659
Strawberry (Fragaria ×ananassa) is a fruit that is rich in bioactive components and nutrients. A previous study revealed that strawberries offer beauty benefits, including anti-inflammatory effects. In this study, we investigated the potential hair growth-promoting properties of strawberries by measuring dehydrogenase activity as an indicator of cellular metabolism, and assessed the expression of hair growth-related genes in human follicle dermal papilla cells (HFDPC). Additionally, we performed chemical analyses to characterize the active compounds contributing to the observed effects. The results indicated that strawberry water-extract promotes the metabolism of HFDPC, and that this effect was reduced with heat treatment. The expression levels of hair growth-related genes (FGF7, VCAN, and TGFB2) were examined, but no significant differences were detected. Although further investigation into the components and mechanisms underlying this bioactivity is required, these results lay a foundation for the development of hair-care cosmetics.
