2026 Volume 32 Issue 2 Pages 179-189
To prevent excess ingestion of salt, methods for reducing the particle size of sodium chloride (NaCl) to promote dissolution are of interest. We investigated anti-solvent crystallization and the addition of seed crystals for reducing particle size, which is typically on the order of several hundred micrometers. Anti-solvent crystallization is suitable for producing crystals measuring <50 µm in size. Therefore, we used a Taylor–Couette (TC) crystallizer that generates small crystals with a uniform particle size to produce seed crystals. The seed crystal slurry was suspended in an anti-solvent. We conducted two experiments by adding the anti-solvent to an NaCl aqueous solution and by adding an NaCl aqueous solution to the anti-solvent. As a result, cubic NaCl crystalline particles with a smooth surface and an average particle size (D50) of 66.5 µm were successfully obtained using a seed crystal slurry prepared via the TC vortex.
