Paraneoplastic Limbic Encephalitis Caused by Ovarian Teratoma with Autoantibodies to Glutamate Receptor

Sadahisa Okamoto; Teruyuki Hirano; Yukitoshi Takahashi; Taro Yamashita; Eiichiro Uyama; Makoto Uchino

doi:10.2169/internalmedicine.46.6466

CASE REPORTS

Paraneoplastic Limbic Encephalitis Caused by Ovarian Teratoma with Autoantibodies to Glutamate Receptor

Sadahisa Okamoto, Teruyuki Hirano, Yukitoshi Takahashi, Taro Yamashita, Eiichiro Uyama, Makoto Uchino

著者情報

キーワード: paraneoplastic limbic encephalitis, ovarian teratoma, glutamate receptor

ジャーナルオープンアクセス

2007 年 46 巻 13 号 p. 1019-1022

DOI https://doi.org/10.2169/internalmedicine.46.6466

詳細

抄録

We report a rare case of paraneoplastic limbic encephalitis with autoantibodies to glutamate receptor (GluR) in the cerebrospinal fluid (CSF). The 35-year-old woman with consciousness disturbance was diagnosed initially as non-herpetic encephalitis. Her signs and symptoms improved with acyclovir and steroid pulse therapy. However, after the treatment, an ovarian tumor was discovered, and we detected autoantibodies to GluR in the CSF. A possible association between the ovarian teratoma and GluR is suggested.

責任著者(Corresponding author)

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