抄録
The purpose of this study was to investigate major indigenous oral bacteria and latent pathogenic microorganisms in the oral cavity of maxillectomy patients. The subjects were patients with maxillectomy （n = 22）, against healthy adult controls with dentures （n = 14） and without dentures （n = 15）. Informed consent was obtained from all subjects prior to the study. In all the examined sites of the tumor group, Candida spp., Staphylococcus spp., MRSA and Pseudomonas spp. showed statistically higher bacterial numbers than in the control groups. When the buccal wall of maxillary defect of the tumor group was compared with the normal buccal mucosa, there were more Staphylococcus spp. and MRSA in the former than in the latter, showing a statistical difference. Furthermore, in the tumor group, the palate had statistically higher numbers of Candida spp. and MRSA than the sinus. These results showed that the latent pathogenic microorganisms such as Candida spp., Staphylococcus spp., MRSA and Pseudomonas spp. colonized in the oral cavity of the maxillectomy patients, especially at the defective sites. Therefore, it is suggested that proper oral hygiene guidance and regular clinical management are fundamental for patients with a maxillary prosthesis, in order to not only improve QOL but also to avoid the risk of critical infection.
