Study on Fasting and Postprandial Changes in Serum TG, T-Cho, HDL-C, PL, AST, ALT, γGTP, BUN, CRE, UA, and TBA Levels

抄録

To study sex differences in preprandial data and their postprandial fluctuations, 65 men and 59 women consumed a meal consisting of 30.9 g of fat, 21.3 g of proteins, and 95.9 g of carbohydrates with total calories of 764.9 KC. Blood specimens were collected before and 2, 3, and 4 hours after the meal.
For the statistical analysis, Dunnett's multiple comparison was used.
Men exhibited higher values for TG, AST, ALT, γGTP, BUN, CRE, and UA, while HDL-C was higher in women. No sex-related difference was noted in the T-Cho, PL, and TBA levels.
Compared with the preprandial values, TG increased with significant differences in both men and women, 2, 3, and 4 hours after the meal. The maximum value was recorded 3 hours after the meal, with an increase of 46.9% for men and 43.0% for women.
Sensitivity and specificity were 92.0% and 92.9%, respectively, when the value 2, 3, and 4 hours after the meal was over 200 mg/dl and the preprandial value was estimated to be over 150 mg/dl.
Compared with the preprandial values, TBA increased in both men and women 2, 3, and 4 hours after the meal. Significant differences were noted for men 2 and 3 hours after the meal. The maximum value was obtained 3 hours after the meal for both genders (increases of 40.6% for men and 39.3% for women) .
The fluctuation curves for TG and TBA of some individuals suggested an effect from meals taken on the previous day. It was con-cluded that the subjects should avoid attending sumptuous affairs-such as parties-on the previous day and blood specimens should be collected before a meal.
Only slight fluctuations were found in the postprandial values for T-Cho, HDL-C, PL, AST, ALT, γGTP, BUN, CRE, and UA. The maximum change from the preprandial value was less than 8.0%.