Journal of Health Science
Online ISSN : 1347-5207
Print ISSN : 1344-9702
ISSN-L : 1344-9702
RESEARCH LETTERS
Disinfection By-Products of para-Hydroxybenzoate Esters (Parabens): Synthesis and Mass Spectrometric Study
Masanori TerasakiMasakazu Makino
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2009 年 55 巻 4 号 p. 631-635

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A simple and efficient procedure for the chlorination of para-hydroxybenzoate esters (parabens) with sulfuryl chloride is described. Fourteen monochlorinated or dichlorinated parabens were synthesized and their mass spectrometric characteristics were determined. This work enabled the definitive identification and quantification of the chlorinated parabens in environmental samples.

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© 2009 by The Pharmaceutical Society of Japan
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