Eisei kagaku
Print ISSN : 0013-273X
Thin-Layer Chromatography of Hypnotics of Barbituric Acid Derivatives.
Tetsukichi Niwaguchi
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1964 Volume 10 Issue 1 Pages 6-8

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Abstract
Separation and identification of several kinds of barbituric acid derivatives by thin-layer chromatography were investigated. The thin-layer was made of a mixture of silicic acid, potato starch and sodium carbonate. The most suitable solvent system among those tested was ethylene dichloride-acetone (85 : 15). Spectroscopic characterization of the compounds submitted to the chromatography was performed by eluting the spots with 0.5 N ethanolic sodium hydroxide.
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© The Pharmaceutical Society of Japan
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