抄録
The influences of developer vapour on thin-layer and dry-column chromatography of several hypnotics were investigated. Experiments on silicagel thin-layer and dry-column chromatography using a developer consisted of 2-propanol, chloroform and ammonia (or water) revealed that the developer vapour induced a modification of the activity of silicagel. A comparable separation by thin-layer and dry-column chromatography was attained by saturation with the developer vapour (or ammonia) or use of silicagel treated with Na2CO3 solution.
