Abstract
Acute and subacute toxicity of dimethylacrylamide in mice was studied. LD50 by a single oral dose was 485 mg/kg (male) and 460 mg/kg (female), and that by subcutaneous injection was 580 mg/kg (male) and 590 mg/kg (female). In a subacute toxicity test for a 6-week period, no adverse change attributable to the ingestion of dimethylacrylamide was observed in body weight, gross physiological appearance, and in clinical, histopathological, and hematological examinations, except a slight increase in the weight of the liver, spleen, and testis.
