Pregnant rats were used for experiment at 20 th day after gestation, which was determined by the presence of a vaginal plug after mating. Sodium selenite[
75Se]solution was given intravenously to a number of pregnant rats and the distribution pattern of
75Se in the mother and fetus was determined by measuring radioactivities 1 hr after injection. In the mother rats, high concentration of
75Se was found in the liver, kidney, pancreas and lung, the concentration being twice higher than that in the blood. The transfer of
75Se to fetus was not so marked but radioactivity 5% of the dose was found in the whole body of a litter. High concentration of
75Se was observed in the liver, adrenal and kidney of the fetuses, concentration of
75Se in the bone, spleen and gastro-intestinal tract was the same as that in the whole body of fetuses.
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