The road landscape from travelling vehicle is a valuable tourist attraction for Hokkaido, because the driving tour becomes popular recently. To increase Hokkaido’s competitiveness in tourism, it is necessary to find what and where regional uniqueness of road internal landscape in Hokkaido is. In this study, the HLI which represents the regional uniqueness of road internal landscape in Hokkaido is devised by the impression test to people living outside Hokkaido and the equation which estimates the HLI form fractal dimension and sky share of a digital road landscape image is developed. It is also demonstrated that sections with high regional uniqueness are extracted and the positive effects of landscape preservation such as elimination of utility poles, electrical cables, billboards, are estimated through the application to the several scenic byway Hokkaido routes which are arterial national roads.