抄録
Japanese valerian is a herbal medicine with a long history that continues from the first edition of the Japanese Pharmacopoeia (JPI) (1886) to the present JPXVI (2011). This research focuses on the standards and test methods of this item in JPI (1886) to JPXVI (2011), and the pharmacological evaluation of this item in Japan was considered while comparing it with the result of transitions of the standards and test methods of European valerian (valerian root) in the United States Pharmacopoeia (USP) described in a previous report and in the British Pharmacopoeia (BP).
It can be said that the standards and tests of this item in today's JPXVI (2011) have been able to maintain quality. However, based on comparison with today's USP and BP, the JPXVI (2011) standards and tests do not reflect the surprising progress in pharmacology that has been made in recent years and do not sufficiently reflect the circumstances of this item that are clarified to some extent in the surrounding information. For these reasons, the pharmacological evaluation of this item in the JP is considered satisfactory. It is thought that there is relatively low demand for this item in Japan compared with the demand for valerian root in Europe and America. That is, it is thought that this item is not highly evaluated in Japan compared to the pharmacological evaluation of European valerian (valerian root) in Europe and America.
It was found that the pharmacological evaluation in Japan has not been high in recent years although this item received high appraisal before World War II worldwide in terms of quality. However, there are expectations for higher evaluations in the future in respect to its effect and safety as a natural medicine.
