薬史学雑誌
Online ISSN : 2435-7529
Print ISSN : 0285-2314
ISSN-L : 0285-2314
珈琲一杯の薬理学 壊血病と浮腫病の歴史に見るコーヒーとビタミンの関係
岡 希太郎
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2016 年 51 巻 1 号 p. 5-10

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Scurvy, a vitamin C deficiency, was rampant during the age of discovery in Europe. In the mid-17th century, Pasqua Rosee, the first coffee house in London, put an ad in the newspaper Publick Adviser clearly stating, It (coffee) is excellent to prevent and cure dropsy, gout, and scurvy. A Netherlands trade merchant carried the information to Nagasaki, Japan, along with coffee beans harvested in the Netherlands’new territory, Java Island. A Japanese physician in Nagasaki, Dr. Kai Hirokawa, translated the information into Japanese in his new book, Dutch Medicines, published in 1803. According to the ancient documents stored in Wakkanai City, Japan, the coffee beans were distributed to Tsugaru Clan soldiers who were guarding the northern coastline from 1855 to 1856. The purpose of the distribution was the prevention of scurvy and dropsy. As the result, none of the soldiers died from scurvy during the winter of 1855-1856. This paper discusses the pharmacological relationship between coffee micronutrients and vitamin deficiency syndrome.

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© 2016 日本薬史学会
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