We evaluated the performance of a 1 million pixel CCD camera developed as an image intensifier based on an X-ray imaging device. The camera can be operated in the progressive mode, generating 30 frames/sec. with 1024 x 1024 matrix. First, we compared CCD's performance, including MTF, noise Wiener spectra, NEQ, with a conventional pick-up tube camera and a cine camera. Then we performed ROC analyses for the CCD camera and the cine camera to explore the possibility of replacing the cine camera with the CCD for cardiac imaging. The CCD's MTF was far superior to the pick-up tube's but slightly inferior to the cine camera. Furthermore, the CCD's MTF remained constant with the input light intensity changed, while the pick-up tube's changed. The CCD's Wiener spectrum was greater than the pick-up tube's in the high frequency region, but lower than the cine camera's throughout the frequency region. In the NEQ, the CCD surpassed the other two cameras, except that it showed a lower NEQ than the cine camera's in the higher frequency region than 1.5 cycles/mm. The ROC analysis showed that for static images, the CCD had superior imagimg to the cine camera, Az being 0.75:0.65 while for dynamic images, the CCD had slightly inferior imagimg, Az being 0.88:0.91.
