日本放射線技術学会雑誌
Online ISSN : 1881-4883
Print ISSN : 0369-4305
ISSN-L : 0369-4305
臨床技術
固形がん治療効果判定法(RECIST)における腫瘍径測定精度の検討
後藤 政実井野 賢司赤羽 正章山下 美和鈴木 雄一今江 禄一長谷川 浩章西田 克次矢野 敬一飯田 恭人美馬 和男大友 邦
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2007 年 63 巻 7 号 p. 774-781

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Image evaluation with Response Evaluation Criteria in Solid Tumors (RECIST) evaluates the change in a measurable lesion as determined by ruler or micrometer caliper. However, there is no definition of the conditions thought to influence the precision of measurement. We therefore examined the effects on measurement precision by changing image amplification, WW, WL, and time phase. Moreover, to determine response rate, one-dimensional evaluation with RECIST was compared with the two-dimensional evaluation of World Health Organization (WHO) for a hepatocellular carcinoma. The results of measuring the object lesion for measured value variation were as follows. Under image conditions of 1 time expansion/ WW 150/ WL 100 was (4.92±1.94)%. Under image conditions of 1 time expansion/ WW 350/ WL 75 was (4.42±1.70)%. Under image conditions of 4 times expansion/ WW 150/ WL 100 was (2.52±0.82)%. Under image conditions of 4 times expansion/ WW 350/ WL 75 was (2.83±1.10)%. When an image was enlarged to 4 times, precision doubled. There was no a difference in comparing RECIST to WHO in terms of response rate. Thus the best method was considered to be RECIST because of its convenience.

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© 2007 公益社団法人 日本放射線技術学会
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