Purpose: The purpose of this study was to investigate the injection pressure reduction effect of the novel indwelling needle (Becton, Dickinson and Company). Method: We evaluated the period of 651 patients who underwent dynamic computed tomography. We compared the maximum injection pressure. The contrast medium was administered at 320, 350, and 370 mgI/ml. Result: The maximum injection pressure of the novel indwelling needle in 22 G was decreased 10% compared with SC5 in all contrast media. The maximum injection pressure of BDN in 20 G decreases 8% compared with SC5 at 370 mgI/ml, but there was no reduction at 320 mgI/ml and 350 mgI/ml. Conclusion: Our analysis demonstrated that BDN significantly reduced the injection pressure especially in 22 G and using high concentration contrast medium in 20 G.