X 染色体分析を実施した高齢男性乳癌の 1 例

抄録

Herein, we report the case of an elderly male patient who was diagnosed as having invasive micropapillary carcinoma (IMPC) of the breast, focusing on the findings of cytology and X-chromosome analysis. The patient presented with a localized solid nodule in the right subareolar region. Cytology revealed cell clusters showing an inside-out pattern in a clean background. The margins of the cell clusters were partially fluffy or showed a microvilli-like pattern. Histologically, the tumor was a combination of invasive ductal carcinoma and IMPC. FISH assay revealed an increase in the number of X chromosomes in 32% of the tumor cells.