妊娠と肥満 第２報

抄録

To elucidate the mechanism which produced the maternal obesity, changes in gastrointestine weight, pancreatic amylase activity and trypsinogen activity were analyzed during pregnancy, lactation and weaning (recovery) periods using mice. Moreover, the preventive effects on maternal obesity by a high protein diet and an examination were studied. The results were as follows;
1) The maternal obesity was observed after weaning.
2) Even after weaning, a higher activity of pancreatic amylase was still observed. On the other hand, a lower activity of pancreatic trypsinogen was rather observed.
3) A hypertrophy of gastrointestine also was observed even after weaning.
4) Both high protein diet and examination were effective for preventing the maternal obesity.