Thermomyces lanuginosus Lipase-Catalyzed Esterification of 9,10-Dihydroxystearic Acid and Monohydric Alcohol

Roila AWANG; Mahiran BASRI; Salmiah AHMAD; Abu Bakar SALLEH

doi:10.5650/jos.54.305

Chemstry & Organic Synthesis

Thermomyces lanuginosus Lipase-Catalyzed Esterification of 9,10-Dihydroxystearic Acid and Monohydric Alcohol

Roila AWANG, Mahiran BASRI, Salmiah AHMAD, Abu Bakar SALLEH

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Keywords: dihydroxystearic acid, esterification, immobilized lipase, Thermomyces lanuginosus

JOURNAL FREE ACCESS

2005 Volume 54 Issue 5 Pages 305-309

DOI https://doi.org/10.5650/jos.54.305

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Abstract

An enzymatic method has been developed for the preparation of dihydroxystearic acid ester in high conversion (∼90%) by esterification of 9,10-dihydroxystearic acid and 1-octanol at moderate temperature (50 °C) using immobilized lipase from Thermomyces lanuginosus (Lipozyme TL IM) as biocatalyst. The effects of enzyme dosage, reaction temperature, reaction time and reusability of the enzyme in esterification were studied.

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