変敗油の毒性 (第11報)

熱酸化重合油に対するトコフェロールの補充効果

抄録

Authors investigated the effect of tocopherol purposing for prevention of the toxicity induced by thermally oxidized oils.
Rats were fed with a diet containing fresh oil and thermally oxidized soybean oils with or without tocopherol.
The results obtained were as follows :
1) The rats fed with thermally oxidized oil showed growth depression and ruffled hair, whereas better growth was observed when the rats were fed on the same oil with tocopherol.
2) Amount of triglycerides in liver lipids was found to be remarkably increased in comparison with those of rats fed with thermally oxidized oil and also found as similar to those of fresh oil.
3) In the fatty acid composition, a significant difference between thermally oxidized oil and tocopherobadded group was observed.
Percentage of linoleate in liver lipids and liver glycerides for the rats fed with thermally oxidized oil added with tocopherol was higher than that of tocopherol-free group.
These results indicate that tocopherol has some antioxidative activity for the oxidation of essential fatty acids in liver.