Synthesis of 1-Dialkylaminoalkylidenediphosphonic Acids and Their Properties for Complex Formation
1976 年 25 巻 6 号 p. 362-364
詳細
1976 年 25 巻 6 号 p. 362-364
1-Dialkylaminoalkylidenediphosphonic acids were obtained by the reaction of N, N-dialkylaliphatic acid amides with phosphorus trichloride, and subsequent treatment with acetic acid.
The dissociation constants (pKa) of these aminodiphosphonic acids were determined from the titration curves. The behavior of dimethylaminomethylenediphosphonic acid and 1-dimethylaminoethylidene-diphosphonic acid toward metal ions was investigated, and it was found that these aminodiphosphonic acids could be utilized for chelating agents.
