油化学
Online ISSN : 1884-2003
ISSN-L : 0513-398X
脂質のDDS機能
平野 二郎日比野 英彦
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ジャーナル フリー

1988 年 37 巻 10 号 p. 864-871

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Lipids as drug carriers influence on parenteral absorption of drags, their intracorporeal distribution, metabolism, and elimination. Especially, lipid vesicles composed of polar lipids, surfactants, and the like, are expected to deliver drugs toward their target sites, and to control their releasing continually. The reason why is that the systems described above is relatively lymphatogenous, so they can aim at their target.
Up to the present, various studies have been carried out on new drug carriers using lipids ; liposomes, lipid micro-sphere, lipid-surfactant mixed micelles, oleous constructive medium etc.
These materials are bioerodible, biocompatible, and non-antigenic.
For some of them, the clinical effects have been examined.
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