下痢性貝毒の構造解析と微量分析
1989 年 38 巻 10 号 p. 815-822
詳細
1989 年 38 巻 10 号 p. 815-822
Diarrhetic shellfish poisoning is a gastro-enteritis caused by eating shellfish infested with polyether toxins of dinoflagellate origins. Three structurally different groups of toxins consisting of eight components have been isolated and their structures were determined. The first group comprising okadaic acid and its derivatives are polyether compounds carboxylic acids having strong diarrheagenisity. The second is a pectenotoxin group which shares a polyether macrolide skeleton. The third group is the newest constituent, yessotoxin, which consists of transfusing ether rings, mimicing the structure of brevetoxins.
